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KMID : 0985520110160020165
Korean Journal of Pancreas and Biliary Tract
2011 Volume.16 No. 2 p.165 ~ p.168
Fasciola Hepatica Infection with Sphincter of Oddi Dysfunction
Ha Kyung-Ho

Kim Ki-Yong
Park Keun-Woo
Kim Myung-Hwan
Bae Gyu-Hwan
Seo Chang-Jin
Han Ji-Min
Kim Ho-Gak
Abstract
Fascioliasis is a zoonotic infection by Fasciloa hepatica, a liver fluke that infests cattle and sheep. Humans are infected by eating water plants contaminated with metacercariae. Fasciola hepatica causes liver abscess, cholangitis, common bile duct obstruction and so on. We report a 42-year-old woman who presented with epigastric pain radiating to back and eosinophilia. During follow-up period, liver function was worsen transiently and abdominal computed tomography showed hypodense area in caudate lobe. She was diagnosed with sphincter of Oddi dysfunction on manometry. Endoscopic sphincterotomy was conducted, but epigastric pain was not changed. Additionally we diagnosed fascioliasis serologically. Triclabendazole, treatment of cholice for fascioliasis, cannot be got all over the world. We have tried albendazole and praziquantel, but clinical improvement was not observed. Recently nitazoxanide was given to her, and we are observing clinical course. This report suggests that sphincter of Oddi dysfunction can be caused by fascioliasis.
KEYWORD
Fascioliasis, Sphincter of Oddi dysfunction
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